In contrast, Wales are on a record run of 11 international defeats and are in danger of losing all 11 matches in 2024 with head coach Warren Gatland under pressure.
“No player or coaches train to lose and I feel for them,” said Kolisi.
“I know they will get out of it. If anybody can get them out of it, it’s coach Gatland.
“He has given a lot of new guys opportunities. It’s a new team. I don’t think we have seen a Welsh team with so few caps.
“Things like that take time and the more they play, the better they will get because it’s giving them a lots of experience.
“I am not too stressed for them because we have been in that situation and you just pull tighter.”
Kolisi believes Gatland’s side need the Welsh rugby public’s backing.
“The way people still support the team and come out in numbers is special,” said Kolisi.
“You feel the pride here because they love the team and that’s the sort of passion you want.
“When you go through a tough time as a playing group, the people go through those tough times with you.”
South Africa have won six of their last seven Tests against Wales after losing four in a row against them previously.
Wales have also been successful in just one of their last 11 Test matches at the Principality Stadium.
“It’s hard to beat them and a lot of us have been beaten here a couple of times,” said Kolisi.
“I know what the score was last week against Australia [52-20] but their forwards got five scrum penalties.
“They have a pack that can stand up against anybody and that’s a great foundation.”