British heavyweight Johnny Fisher will fight Andriy Rudenko at the Copper Box Arena in London on 28 September.
The fight card will include an all-British world title fight between WBO lightweight champion Rhiannon Dixon and Terri Harper.
Both bouts were due to be on the undercard of Dalton Smith’s cancelled lightweight fight against Jon Fernandez in Sheffield.
It is the second time Fisher has headlined at the Copper Box Arena, having stopped Alen Babic in July.
The one-round victory was the 11th knockout win for the undefeated Romford fighter.
Fisher, 25, faces a vastly more experienced opponent in 40-year-old Rudenko.
The Ukrainian has 36 wins and seven defeats on his record, including to American Jared Anderson, China’s Zhilei Zhang and Briton Hughie Fury.
For Dixon, this is the second time her first world title defence has been moved after it was originally scheduled for 23 August on the undercard of Jack Catterall v Regis Prograis in Manchester.
Dixon, 29, is undefeated in 10 fights and will make a first defence of the world title she won in April.
Harper, 27, is a multiple-weight world champion with 14 wins, two losses and two draws on her impressive record.
But the Doncaster fighter has had mixed fortunes in her most recent bouts, drawing with Cecilia Braekhus in a light-middleweight unification fight last October, before suffering a stoppage loss to WBO champion Sandy Ryan at welterweight in March.
Dixon is one of two currently undefeated world champions from England alongside WBA featherweight champion Nick Ball.