In the Europa League, which follows the same format as the Champions League, AZ Alkmaar face Galatasaray and Midtjylland will play Real Sociedad in the play-offs.
The winners of those ties will face either Manchester United or Tottenham Hotspur in the last 16.
Twente will play Bodo/Glimt and Jose Mourinho’s Fenerbahce have been drawn against Anderlecht, with one of the winners of those two ties then facing Rangers.
United and Spurs were third and fourth in the 36-team Europa League group stage respectively, and with Rangers finishing eighth it meant all three British sides qualified automatically for the last 16.
Notable ties include two-time winners Porto playing 1984 European Cup finalists Roma, while Hungarian side Ferencvaros – managed by former Tottenham striker Robbie Keane – play Viktoria Plzen.
The winners of those two ties will be drawn against either Lazio or Athletic Bilbao.
As with the Champions League, the last-16 draw will be made on 21 February once the eight winners of the play-off ties are known. That will complete the brackets and teams will know their routes to the final.
The two-legged play-off ties are on 13 and 20 February, with the last-16 matches scheduled for 6 and 13 March.
