Wiese’s final campaign at Tigers started after helping South Africa defend their World Cup crown in France.
He misses out on a glorious ending with Leicester, with Tigers eighth in the table and 12 points adrift of the play-off spots after a difficult first campaign under Australian head coach Dan McKellar.
Asked what he wants from his final match in a Tigers shirt, Wiese said: “A win.”
But Wiese, who was named newcomer of the year in his first campaign and was voted players’ player of the season for the 2023-24 campaign on Tuesday, wants to do more than just savour one last victory.
“It has been a tough year for this group, with a few results not going our way,” he said.
“For me, personally, it’s just for the group to enjoy it as much as they can and to not even worry about the result.
“There are a few guys leaving, so really enjoying the last few days we have together, the last game we have together, is the biggest thing.”