Speaking in Abidjan on Friday, Motsepe also insisted he is confident this year’s Afcon will not see a repeat of the kind of tragedy which marred the last tournament in Cameroon.
Eight people were killed and dozens injured in a crush and stampede at the Olembe Stadium in Yaounde prior to the last-16 match between the hosts and Comoros.
The Ivorian government has invested over $1.5 billion in improving infrastructure in order to host the tournament for the first time since 1984.
That has included the construction of the 60,000-capacity Alassane Ouattara Olympic Stadium, on the northern outskirts of Abidjan, which will host Saturday’s opening game as well as the final on 11 February.
There will be around 17,000 police and soldiers deployed during the month-long tournament to ensure security.
“I am satisfied the appropriate steps have been taken to make sure we will totally avoid the painful experience we had in Cameroon,” added Motsepe.
“The Cameroon accident was absolutely avoidable.
“For as long as I am president, whether I know or don’t know, whether I am aware or not aware, I ultimately have to take responsibility for anything that happens.
“I am satisfied that there is a huge amount of determination and commitment and I think we are on the right track.”